T-CELL DEVELOPMENT IN THE FETUS AND THE INVARIANT SERIES HYPOTHESIS

被引：19

作者：

ASPINALL, R

KAMPINGA, J

VANDENBOGAERDE, J

机构：

[1] DEPT HISTOL,GRONINGEN,NETHERLANDS

[2] ADDENBROOKES HOSP,DEPT SURG,CAMBRIDGE CB2 2QQ,ENGLAND

来源：

IMMUNOLOGY TODAY | 1991年 / 12卷 / 01期

关键词：

D O I：

10.1016/0167-5699(91)90105-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Comparison of the timing of appearance of certain T-cell markers in the intrathymic development of T cells during gestation reveals a common sequence of expression in several species. Here Richard Aspinall and colleagues put forward a hypothesis concerning this 'invariant series' of markers that shares the same timing of expression across species barriers. It is proposed that T-cell markers that are members of the invariant series are very important in deciding the fate of a developing thymocyte.

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页码：7 / 10

页数：4

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