BRAIN-LESIONS IN PATIENTS WITH MULTIPLE-SCLEROSIS - DETECTION WITH ECHO-PLANAR IMAGING

被引:26
作者
SIEWERT, B [1 ]
PATEL, MR [1 ]
MUELLER, MF [1 ]
GAA, J [1 ]
DARBY, DG [1 ]
POSER, CM [1 ]
WIELOPOLSKI, PA [1 ]
EDELMAN, RR [1 ]
WARACH, S [1 ]
机构
[1] HARVARD UNIV,BETH ISRAEL HOSP,SCH MED,DEPT NEUROL,BOSTON,MA 02215
关键词
BRAIN NEOPLASMS; MR; MAGNETIC RESONANCE (MR); COMPARATIVE STUDIES; ECHO PLANAR; SCLEROSIS; MULTIPLE;
D O I
10.1148/radiology.196.3.7644641
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
PURPOSE: To evaluate the detection of brain lesions with echo-planar imaging relative to conventional spinecho(SE)imaging. MATERIALS AND METHODS: In 17 patients (three men, 14 women; mean age, 31 years) with multiple sclerosis, the following were compared: single-shot proton-density- and T2-weighted and thin-section T2-weighted echo-planar, proton-density- and T2-weighted multishot echo-planar, and conventional SE sequences. Quantitative and qualitative criteria as well as lesion detectability were evaluated. The proton-density-weighted SE sequence was used as the standard of reference. RESULTS: Multishot sequences were superior to single-shot sequences in image quality and lesion detectability. With the multishot proton-density-weighted sequence, 53 of 54 large lesions and 23 of 30 small lesions were detected; with the single-shot proton-density-weighted sequence, 38 of 54 large lesions and five of 30 small lesions were detected. CONCLUSION: With multishot echo-planar sequences, detectability of large lesions is similar to that with conventional SE imaging. Susceptibility artifact is diminished in comparison to single-shot echo-planar sequences.
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页码:765 / 771
页数:7
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