ESTIMATION OF PLASMA RENIN CONCENTRATION USING RADIOIMMUNOASSAY OF ANGIOTENSIN-II

被引：31

作者：

POULSEN, K

机构：

来源：

SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION | 1969年 / 24卷 / 03期

关键词：

Angiotensin-I; Angiotensin-II; Converting enzyme; Enzyme assay; Enzyme kinetics; Plasma renin activity; Plasma renin concentration; Radio-immunoassay; Renin-substrate;

D O I：

10.3109/00365516909080165

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Renin is measured by the rate of renin-substrate consumption with time. Renin-substrate is measured by conversion to angiotensin-II by excess of renin and converting enzyme. Characteristics: precisely determined angiotensinogen conc. during reaction, controlled converting enzyme activity, and eliminated influence of angiotensinases. The method, using 300 μl plasma, gives simultaneously renin concentration, renin activity, and renin-substrate concentration without chromatographic steps. Detection limit is 22 times lower than normal mean. Precision ± 6 %. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：291 / &

共 22 条

[1] ALEXANDRE JM, 1967, REV FR ETUD CLIN BIO, V12, P492
[2] BING J, 1969, ACTA PATHOL MIC SC, V75, P33
[3] Bojesen E., 1966, EUR J STEROIDS, V1, P145
[4] A MICROMETHOD FOR MEASUREMENT OF RENIN IN PLASMA AND KIDNEY OF RATS
BOUCHER, R
MENARD, J
GENEST, J
[J]. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1967, 45 (05) : 881 - &
[5] BOYD GW, 1969, LANCET, V1, P213
[6] IMMUNOLOGICAL REACTIVITY OF PEPTIDES RELATED TO ANGIOTENSIN
CATT, KJ
COGHLAN, JP
ROMBERG, B
[J]. NATURE, 1967, 215 (5099) : 395 - &
[7] IMMUNOCHEMICAL ANALYSIS OF RABBIT ANTIBODIES AGAINST ANGIOTENSIN 2
DIETRICH, FM
[J]. IMMUNOCHEMISTRY, 1967, 4 (02): : 65 - &
[8] MEASUREMENT OF PLASMA ANGIOTENSIN 2 AND CORRELATION WITH RENIN ACTIVITY
GOCKE, DJ
SHERWOOD, LM
OPPENHOFF, I
GERTEN, J
LARAGH, JH
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1968, 28 (11) : 1675 - +
[9] IMMUNOCHEMICAL STUDIES OF ANGIOTENSIN
GOODFRIEND, T
FASMAN, G
KEMP, D
LEVINE, L
[J]. IMMUNOCHEMISTRY, 1966, 3 (03): : 223 - +
[10] HAAS E, 1968, LANCET, V1, P657

← 1 2 3 →