INFANT-FEEDING IN FINNISH CHILDREN LESS-THAN-7-YRS-OF-AGE WITH NEWLY DIAGNOSED IDDM

被引:149
作者
VIRTANEN, SM
RASANEN, L
ARO, A
LINDSTROM, J
SIPPOLA, H
LOUNAMAA, R
TOIVANEN, L
TUOMILEHTO, J
AKERBLOM, HK
机构
[1] UNIV HELSINKI,CHILDRENS HOSP,DEPT PEDIAT 2,SF-00100 HELSINKI 10,FINLAND
[2] NATL PUBL HLTH INST,DEPT BIOCHEM,SF-00280 HELSINKI 28,FINLAND
[3] NATL PUBL HLTH INST,DEPT EPIDEMIOL,SF-00280 HELSINKI 28,FINLAND
关键词
D O I
10.2337/diacare.14.5.415
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: We studied associations between the type of feeding in infancy and the incidence of insulin-dependent diabetes mellitus (IDDM). Research Design and Methods: We studied 103 newly diagnosed diabetic children < 7 yr of age and 103 age- and sex-matched population-based control children in a countrywide study. Results: The risk of IDDM was decreased (P < 0.05) among children breast-fed for at least 7 mo (odds ratio [OR] 0.45, 95% confidence interval [Cl] 0.24-0.85) or exclusively breast-fed for at least 3 (OR 0.33, 95% Cl 0.13-0.84) or 4 (OR 0.43, 95% Cl 0.22-0.84) mo. Also, children who were greater-than-or-equal-to 4 mo old at the time of introduction of supplementary milk feeding had a lower risk of diabetes (OR 0.48, 95% Cl 0.26-0.91). Conclusions: The protective effects of a long duration of breast-feeding and a late introduction of dairy products on the risk of IDDM remained significant after adjusting for the mother's education.
引用
收藏
页码:415 / 417
页数:3
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