MOLECULAR AND CELLULAR BIOLOGY OF RODENT MAST-CELLS

被引：7

作者：

CASTELLS, M

KATZ, HR

AUSTEN, KF

机构：

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY | 1992年 / 99卷 / 2-4期

关键词：

BONE MARROW-DERIVED MAST CELL; FC-GAMMA-R; GLYCOPROTEIN; GLYCOSPHINGOLIPID; MAST CELL; MAST CELL PRECURSOR; PROTEASE; PROTEOGLYCAN; RODENT;

D O I：

10.1159/000236246

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Mouse bone marrow-derived mast cells (BMMC) are progenitors for mucosal mast cells (MMC) and connective tissue mast cells (CTMC). These populations differ in their expression of granule mediators and surface markers. Molecular cloning of most of the components of mast cell granules has provided an essential tool for understanding mast cell heterogeneity and development. Cytokine regulation of mast cell protease gene expression has facilitated the in vitro characterization of the pathways of mast cell maturation towards the CTMC and MMC phenotypes.

引用

页码：189 / 195

页数：7

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