DNAS OF THE 2 MATING-TYPE ALLELES OF NEUROSPORA-CRASSA ARE HIGHLY DISSIMILAR

被引：155

作者：

GLASS, NL ^{[1
]}

VOLLMER, SJ ^{[1
]}

STABEN, C ^{[1
]}

GROTELUESCHEN, J ^{[1
]}

METZENBERG, RL ^{[1
]}

YANOFSKY, C ^{[1
]}

机构：

[1] STANFORD UNIV, DEPT BIOL SCI, STANFORD, CA 94305 USA

来源：

SCIENCE | 1988年 / 241卷 / 4865期

关键词：

D O I：

10.1126/science.2840740

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The mating-type alleles A and .alpha. of Neurospora crassa control mating in the sexual cycle and function in establishing heterokaryon incompatibility in the vegetative cycle. The A and a alleles were cloned, and they were shown to encode both the sexual functions and vegetative incompatibility. The mating-type clones contain nonhomologous DNA segments that are flanked by common DNA sequences. Neurospora crassa and all heterothallic and pseudohomothallic Neurospora species contain a single copy of one mating-type sequence or the other within each haploid genome. The six known self-fertile homothallic isolates contain an A homolog, but only one species also contains a homologous sequence. Homothallism in these species is not due to mating-type switching, as it is in Saccharomyces cerevisiae.

引用

页码：570 / 573

页数：4

共 20 条

[1] A TECHNIQUE FOR RADIOLABELING DNA RESTRICTION ENDONUCLEASE FRAGMENTS TO HIGH SPECIFIC ACTIVITY
FEINBERG, AP
VOGELSTEIN, B
[J]. ANALYTICAL BIOCHEMISTRY, 1983, 132 (01) : 6 - 13
[2] HETEROCARYOSIS AND PROTOPLASMIC INCOMPATIBILITY IN NEUROSPORA-CRASSA
GARNJOBST, L
WILSON, JF
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1956, 42 (09) : 613 - 618
[3] GRIFFITHS AJF, 1978, GENETICS, V88, P239
[4] NULL MUTANTS OF THE A-MATING AND A-MATING TYPE ALLELES OF NEUROSPORA-CRASSA
GRIFFITHS, AJF
[J]. CANADIAN JOURNAL OF GENETICS AND CYTOLOGY, 1982, 24 (02): : 167 - 176
[5] Herskowitz I., 1981, The Molecular Biology of the Yeast Saccharoayces, V.l, P181
[6] DETERMINATION OF THE YEAST-CELL LINEAGE
KLAR, AJS
[J]. CELL, 1987, 49 (04) : 433 - 435
[7] NEW HOMOTHALLIC NEUROSPORAS FROM TROPICAL SOILS
MAHONEY, DP
HUANG, LH
BACKUS, MP
[J]. MYCOLOGIA, 1969, 61 (02) : 264 - &
[8] MANIATIS T., 1982, MOL CLONING LABORATO
[9] IDENTIFICATION AND CHROMOSOMAL DISTRIBUTION OF 5S RIBOSOMAL-RNA GENES IN NEUROSPORA-CRASSA
METZENBERG, RL
STEVENS, JN
SELKER, EU
MORZYCKAWROBLEWSKA, E
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (07) : 2067 - 2071
[10] METZENBERG RL, 1987, FUNGAL GENET NEWSL, V34, P39

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