TRISOMY-12 IN UTERINE LEIOMYOMAS - A NEW CYTOGENETIC SUBGROUP

被引：52

作者：

NILBERT, M

HEIM, S

MANDAHL, N

FLODERUS, UM

WILLEN, H

MITELMAN, F

机构：

[1] UNIV LUND HOSP, DEPT GYNECOL, S-22185 LUND, SWEDEN

[2] UNIV LUND HOSP, DEPT CLIN PATHOL, S-22185 LUND, SWEDEN

来源：

CANCER GENETICS AND CYTOGENETICS | 1990年 / 45卷 / 01期

关键词：

D O I：

10.1016/0165-4608(90)90067-K

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Chromosome analysis of short-term cultures from uterine leiomyomas revealed trisomy 12 in six cases. In four of the tumors + 12 was the only karyotypic change. The fifth case also had trisomy 4, whereas the sixth had loss of one X chromosome as an additional aberration. These findings indicate that trisomy 12 characterizes a new cytogenetic subgroup of uterine leiomyoma. © 1990.

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页码：63 / 66

页数：4

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