OSTEOPOROSIS IN RHEUMATOID-ARTHRITIS - EFFECT OF DISEASE-ACTIVITY

被引：29

作者：

CELIKER, R

GOKCEKUTSAL, Y

CINDAS, A

ARIYUREK, M

RENDA, N

KORAY, Z

BASGOZE, O

机构：

[1] Department of Physical Medicine and Rehabilitation, Hacettepe University, School of Medicine, Ankara

[2] Department of Radiology, Hacettepe University, School of Medicine, Ankara

[3] Department of Biochemistry, Hacettepe University, School of Medicine, Ankara

[4] Department of Nuclear Medicine, Hacettepe University, School of Medicine, Ankara

来源：

CLINICAL RHEUMATOLOGY | 1995年 / 14卷 / 04期

关键词：

RHEUMATOID ARTHRITIS; OSTEOPOROSIS; BONE DENSITOMETRY;

D O I：

10.1007/BF02207677

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In addition to juxtaarticular osteoporosis, which appears to reflect predominantly local disease mechanisms, more generalized bone loss can occur in rheumatoid arthritis(RA), The aim of this study was to compare bone mineral density (BMD) of the lumbar spine and proximal femur in RA patients versus controls and evaluate the influence of disease related determinants. Twenty-seven patients with RA and twenty healthy subjects were included in this study, BMD was significantly reduced in RA patients compared with the control group, BMD was correlated with duration of disease, health assessment questionnaire scores, hand grip strength and erythrocyte sedimentation rate. These results support the hypothesis that BMD may be affected by RA related determinants.

引用

页码：429 / 433

页数：5

共 28 条

[1]

Laan R.F.J.M., Buijs W.C.A.M., Verbeek MA.L.M., Draad M.P., Corstens F.H.F., Van de Putte L.B.A., Van Riel P.L.C.M., Bone mineral density in patients with recent onset rheumatoid arthritis: Influence of disease activity and functional capacity, Ann Rheum Dis, 52, pp. 21-26, (1993)

[2]

Pietschmann P., Machold K.P., Wolosczuk W., Smolen J.S., Serum osteocalcin concentrations in patients with rheumatoid arthritis, Ann Rheum Dis, 48, pp. 654-657, (1989)

[3]

Sambrook P.N., Eisman J.A., Champion G.D., Yeates M.G., Pocock N.A., Eberl S., Determinants of axial bone loss in rheumatoid arthritis, Arthritis Rheum, 30, pp. 721-728, (1987)

[4]

Hall G.M., Spector T.D., Griffin A.J., Jawad A.S.M., Hall M.L., Doyle D.V., The effect of rheumatoid arthritis and steroid therapy on bone density in postmenopausal women, Arthritis Rheum, 36, pp. 1510-1516, (1993)

[5]

Jones S.M., Bhalla A.K., Osteoporosis in rheumatoid arthritis, Clin Exp Rheumatol, 11, pp. 557-567, (1993)

[6]

Laan R.F.J.M., Van Riel P.L.C.M., Van de Putte L.B.A., Bone mass in patients with rheumatoid arthritis, Ann Rheum Dis, 51, pp. 826-832, (1992)

[7]

Garton M.J., Reid D.M., Bone mineral density of the hip and of the anteroposterior and lateral dimensions of the spine in men with rheumatoid arthritis, Arthritis Rheum, 36, pp. 222-228, (1993)

[8]

Laan R.F.J.M., Van Riel P.L.C.M., Van Erning L.J.T.O., Lemmens J.A.M., Ruijs S.H.J., Van de Putte L.B.A., Vertebral osteoporosis in rheumatoid arthritis patients: Effect of low dose prednisone therapy, Br J Rheumatol, 31, pp. 91-96, (1992)

[9]

Kalla A.A., Meyers O.L., Chalton D., Heath S., Brown M.M., Smith P.R., Burger M.C., Increased metacarpal bone mass following 18 months of slow-acting antirheumatic drugs for rheumatoid arthritis, Br J Rheumatol, 30, pp. 91-100, (1991)

[10]

Michel B.A., Bloch D.A., Fries J.F., Predictors of fracture in early rheumatoid arthritis, J Rheumatol, 18, pp. 804-808, (1991)

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