POTENTIAL COENZYME INHIBITORS .2. REDUCTION OF 4-METHYLNICOTINAMIDE DERIVATIVES BY SODIUM DITHIONITE AND SODIUM BOROHYDRIDE

被引：28

作者：

LOVESEY, AC

ROSS, WCJ

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY B-PHYSICAL ORGANIC | 1969年 / 02期

关键词：

D O I：

10.1039/j29690000192

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The preparation of some 4-methylnicotinamide derivatives is described, and the dithionite and borohydride reduction products are compared with those from the corresponding nicotinamide derivatives. The u.v. absorption and 1H n.m.r. spectra show that in each case 1,4-dihydronicotinamides are formed from the dithionite reactions, whilst borohydride reductions yield 1,6-dihydro-derivatives.

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页码：192 / &

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