NG-011 AND NG-012, NOVEL POTENTIATORS OF NERVE GROWTH-FACTOR .1. TAXONOMY, ISOLATION, AND PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES

被引：22

作者：

ITO, M ^{[1
]}

MARUHASHI, M ^{[1
]}

SAKAI, N ^{[1
]}

MIZOUE, K ^{[1
]}

HANADA, K ^{[1
]}

机构：

[1] TAISHO PHARMACEUT CO LTD,RES CTR,1-403 YOSHINO CHO,OMIYA,SAITAMA 330,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1992年 / 45卷 / 10期

关键词：

D O I：

10.7164/antibiotics.45.1559

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

NG-011 and NG-012, novel potentiators of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542, together with 3,4 dihydro-6,8-dihydroxy-3-methylisocoumarin. They potentiated the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12).

引用

页码：1559 / 1565

页数：7

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