VIRAL ONCOPROTEIN BINDING TO PRB, P107, P130, AND P300

被引：54

作者：

LUDLOW, JW

SKUSE, GR

机构：

[1] UNIV ROCHESTER,SCH MED & DENT,DEPT BIOCHEM,ROCHESTER,NY 14642

[2] UNIV ROCHESTER,SCH MED & DENT,DEPT MED,ROCHESTER,NY 14642

来源：

VIRUS RESEARCH | 1995年 / 35卷 / 02期

关键词：

TUMOR SUPPRESSOR GENE; ONCOPROTEIN; GROWTH REGULATORY PROTEIN;

D O I：

10.1016/0168-1702(94)00094-S

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The purpose of this review is to bring attention to some additional work in the tumor virus/tumor suppressor field which may have been overshadowed by reports describing adenovirus, SV40, and HPV oncoprotein binding to pRB and p53. The data reviewed herein provide further support for the model that a common mechanism by which DNA tumor viruses transform cells involves inactivation of cellular proteins which function as negative regulators of cell growth.

引用

页码：113 / 121

页数：9

共 47 条

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