ANTITUMOR COMPONENTS ISOLATED FROM THE CHINESE HERBAL MEDICINE COIX LACHRYMA-JOBI

被引：77

作者：

NUMATA, M

YAMAMOTO, A

MORIBAYASHI, A

YAMADA, H

机构：

[1] NATL INST HLTH, DEPT SAFETY RES BIOL, SHINJUKU KU, TOKYO 162, JAPAN

[2] NATL INST HLTH, DEPT MED ENTOMOL, SHINJUKU KU, TOKYO 162, JAPAN

[3] YAKULT CENT INST MICROBIOL RES, KUNITACHI, TOKYO 186, JAPAN

来源：

PLANTA MEDICA | 1994年 / 60卷 / 04期

关键词：

COIX LACHRYM-JOBI L VAR MA-YUEN STAPF; GRAMINEAE; ANTITUMOR ACTIVITY; FREE FATTY ACIDS; OLEIC ACID; STEARIC ACID; PALMITIC ACID; LINOLEIC ACID;

D O I：

10.1055/s-2006-959500

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The seeds of the gramineous plant Coh lachryma-jobi L. var. ma-yuen Stapf are a traditional Chinese medicine possessing antitumor activity. An acetone extract of the seeds was fractionated by the aqueous alkali method and by silica gel column chromatography in order to identify the antitumor components. Antitumor activity, as assayed by an in vivo growth inhibition test on a transplantable mouse tumor, was attributed to an acidic fraction. Infrared spectroscopy and gas-liquid chromatography showed that this acidic fraction was composed of four free fatty acids: palmitic, stearic, oleic, and linoleic acids.

引用

页码：356 / 359

页数：4

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