PURIFICATION AND CDNA SEQUENCE OF A MURINE PROTEIN HOMOLOGOUS TO THE HUMAN P62 TYROSINE PHOSPHOPROTEIN THAT ASSOCIATES WITH THE RAS GTPASE-ACTIVATING PROTEIN P120 GAP

被引：3

作者：

AGGER, R

FREIMUTH, P

机构：

[1] BROOKHAVEN NATL LAB,DEPT BIOL,UPTON,NY 11973

[2] ODENSE UNIV,DEPT MED MICROBIOL,DK-5000 ODENSE C,DENMARK

来源：

GENE | 1995年 / 158卷 / 02期

关键词：

DENDRITIC CELL; GRANULAR ANTIGEN; AFFINITY PURIFICATION; PEPTIDE SEQUENCING;

D O I：

10.1016/0378-1119(95)00040-D

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A 68-kDa protein that binds to the murine dendritic cell-specific monoclonal antibody M342 was purified and its amino acid sequence was partially determined. Corresponding cDNA clones code for a protein that is closely related to a 62-kDa human protein (p62) that associates with the Ras GTPase-activating protein, p120 GAP, suggesting that p62 may have a dendritic cell-specific function or that an M342 cross-reactive epitope may exist on the murine p62 molecule.

引用

页码：307 / 308

页数：2

共 7 条

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