METABOLISM OF 11-DEHYDROCORTICOSTERONE BY FROG ADRENAL GLANDS

被引：9

作者：

DENICOLA, AF

KRAULIS, I

BIRMINGHAM, MK

机构：

[1] Allan Memorial Institute, Psychiatry McGill University, Montreal

来源：

STEROIDS | 1968年 / 11卷 / 02期

关键词：

D O I：

10.1016/0039-128X(68)90006-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bull frog adrenals metabolize 11-dehydrocorticosterone (21-hydroxypregn-4-ene-3, 11,20-trione) to several polar end products in vitro; these do not include aldosterone (11β,21-dihydroxypregn-4-ene-3, 20-dione-18-al) or 18-hydroxy-11-dehydrocorticosterone (18,21-dihydroxypregn-4-ene-3, 11,20-trione). One major metabolite was tentatively characterized as tetrahydro-11-dehydrocorticosterone (3α,21-dihydroxy-5β-pregnane-11,20 dione). © 1968.

引用

页码：165 / +

页数：1

共 20 条

[1]

BURTON RB, 1951, J BIOL CHEM, V188, P763

[2] METHODS OF PAPER CHROMATOGRAPHY OF STEROIDS APPLICABLE TO THE STUDY OF STEROIDS IN MAMMALIAN BLOOD AND TISSUES [J].