INFLUENCE OF CHLORIDE IONS AND ATP-MG++ ON RELEASE OF CATECHOLAMINES FROM ISOLATED ADRENAL MEDULLARY GRANULES

被引：19

作者：

LISHAJKO, F

机构：

[1] Department of Physiology, Faculty of Medicine, Karolinska Institutet, Stockholm

来源：

ACTA PHYSIOLOGICA SCANDINAVICA | 1969年 / 75卷 / 1-2期

关键词：

D O I：

10.1111/j.1748-1716.1969.tb04378.x

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Carlsson et al. (1963) and Kirshner (1962) have shown that ATP‐Mg stimulates uptake of amines in isolated adrenal medullary granules. This finding has been confirmed (Lishajko 1968) and in addition it was shown that ATP‐Mg inhibits the “spontaneous” release of amines when phosphate buffer was used as medium. On the other hand Oka et al. (1966), Poisner and Trifaro (1967) have reported that ATP‐Mg in certain incubation media increases the release rate of catecholamines in isolated chromaffin granules. In the present communication it will be shown that the releasing effect of ATP‐Mg is dependent on the presence of chloride ions in the medium. © 1969 Scandinavian Physiological Society

引用

页码：255 / &