OCCURRENCE OF GAMMA-GLUTAMYLPHENYLALANINE IN THE URINE OF NEWBORN PHENYLKETONURICS

被引：13

作者：

PECK, H

POLLITT, RJ

机构：

[1] MIDDLEWOOD HOSP,MRC,METAB STUDIES PSYCHIAT UNIT,SHEFFIELD S6 1TP,ENGLAND

[2] SHEFFIELD POLYTECH,DEPT BIOL SCI,SHEFFIELD S1 1WB,S YORKSHIRE,ENGLAND

来源：

CLINICA CHIMICA ACTA | 1979年 / 94卷 / 03期

关键词：

D O I：

10.1016/0009-8981(79)90070-6

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The urine of untreated phenylketonurics in the first weeks of life contains γ-glutamylphenylalanine (0.07-0.69 mmol/g creatinine, 12 samples) visible on the normal 2-dimensional electrophoreto-chromatogram. This compound is less prominent or absent when urine from older untreated phenylketonurics is examined and is not seen in normal urine. © 1979.

引用

页码：237 / 240

页数：4

共 7 条

[1]

BEALE D, 1969, CHROMATOGRAPHIC ELEC, P201

[2] SURVEY OF OCCURRENCE OF BETA-ALANYL-TYROSINE, GAMMA-GLUTAMYL-PHENYLALANINE AND TYROSINE-OMICRON-PHOSPHATE IN LARVAL STAGE OF FLIES (DIPTERA) [J].

BODNARYK, RP .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, 1972, 43 (3B) :587-&

[3] OCCURRENCE OF BETA-ASPARTYL AND GAMMA-GLUTAMYL OLIGOPEPTIDES IN HUMAN URINE [J].

BUCHANAN, DL ;

MARKIW, RT ;

HALEY, EE .

BIOCHEMISTRY, 1962, 1 (04) :612-&

[4]

Gray W.R., 1967, METHODS ENZYMOL, V11, P139, DOI [10.1016/S0076-6879(67)11014-8, DOI 10.1016/S0076-6879(67)11014-8]

[5] DIFFERENTIATION OF ALPHA-AMINO-ACIDS AND AMINES BY NON-ENZYMATIC TRANSAMINATION ON PAPER CHROMATOGRAMS [J].

KALYANKAR, GD ;

SNELL, EE .

NATURE, 1957, 180 (4594) :1069-1070

[6] ISOLATION AND IDENTIFICATION OF L-BETA-ASPARTYL-L-LYSINE AND L-GAMMA-GLUTAMYL-L-ORNITHINE FROM NORMAL HUMAN URINE [J].

LOU, MF .

BIOCHEMISTRY, 1975, 14 (15) :3503-3508

[7] GLUTATHIONE AND RELATED GAMMA-GLUTAMYL COMPOUNDS - BIOSYNTHESIS AND UTILIZATION [J].

MEISTER, A ;

TATE, SS .

ANNUAL REVIEW OF BIOCHEMISTRY, 1976, 45 :559-604

← 1 →