SYNTHESES OF 6-GUANIDINO-HEXOSES AND 5-GUANIDINO-PENTOSES

被引：8

作者：

WESSEL, HP

机构：

[1] Pharma Division, Preclinical ResearchF-Hoffmann-La Roche Ltd.

来源：

JOURNAL OF CARBOHYDRATE CHEMISTRY | 1993年 / 12卷 / 08期

关键词：

D O I：

10.1080/07328309308020126

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Guanidinations of primary amines were performed with 3,5-dimethylpyrazolylformamidinium nitrate. 6-Deoxy-6-guanidino derivatives of unprotected N-acetyl-glucosamine and of glucosamine were prepared, with both products existing as pyranoses. In the pentose series, 5-deoxy-5-guanidinio-D-xylose nitrate (17) and -D-arabinose nitrate (22) were synthesized. For both compounds, besides some alpha-D-xylo-pyranose and beta-D-arabino-pyranose, mainly the furanoses are found.

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页码：1173 / 1186

页数：14

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