USE OF A PROTECTING GROUP IN SYNTHESIS OF 9-ALKYL-9H-PURINE-6(1H)-THIONES

被引：10

作者：

CARROLL, FI

PHILIP, A

机构：

[1] Chemistry and Life Sciences Laboratory, Research Triangle Institute, Research Triangle Park

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1968年 / 33卷 / 10期

关键词：

D O I：

10.1021/jo01274a020

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new synthesis of 9-alkyl-9H-purine-6(1H)-thiones (I) is described which involves the direct alkylation of 6-diphenylmethylthiopurine followed by subsequent removal of the S-diphenylmethyl group. © 1968, American Chemical Society. All rights reserved.

引用

页码：3776 / &

共 6 条

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[3] SYNTHESIS OF POTENTIAL ANTICANCER AGENTS .9. 9-ETHYL-6-SUBSTITUTED-PURINES [J].

MONTGOMERY, JA ;

TEMPLE, C .

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[4] SYNTHESIS AND ANTITUMOR ACTIVITY OF 9-SUBSTITUTED NITROGEN MUSTARD DERIVATIVES OF 6-ALKYLTHIOPURINES [J].

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JOURNAL OF MEDICINAL CHEMISTRY, 1965, 8 (02) :182-&

[5] POTENTIAL PURINE ANTAGONISTS .4. SYNTHESIS OF SOME 9-METHYL-6-SUBSTITUTED-PURINES [J].

ROBINS, RK ;

LIN, HH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1957, 79 (02) :490-494

[6]

1967, 19 AM CHEM SOC SOUTH

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