POLYFLUOROHETEROCYCLIC COMPOUNDS .X. 2,3,5,6-TETRAFLUORO-4-METHYLPYRIDINE AND RELATED COMPOUNDS

被引：18

作者：

CHAMBERS, RD

IDDON, B

MUSGRAVE, WK

CHADWICK, L

机构：

[1] University Science Laboratories, Durham, South Road

来源：

TETRAHEDRON | 1968年 / 24卷 / 02期

关键词：

D O I：

10.1016/0040-4020(68)88036-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The hydrogen atoms of the Me group in tetrafluoro-4-methylpyridine (I) are much less acidic than those of 4-picoline because of the Iπ effect of the fluorine atoms in positions 3 and 5. Free radical halogenation of the side chain of I occurs less readily than for 4-picoline and the resulting di- and trichloromethyl-tetrafluoropyridines can be hydrolysed to the corresponding aldehyde and acid. © 1968.

引用

页码：877 / &

共 21 条

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