POSTSYNAPTIC LOCALIZATION OF THE ALPHA RECEPTOR-MEDIATED STIMULATION OF PHOSPHATIDYLINOSITOL TURNOVER IN PINEAL-GLAND

被引:75
作者
SMITH, TL
EICHBERG, J
HAUSER, G
机构
[1] HARVARD UNIV,SCH MED,SCH MED,DEPT BIOL CHEM,BOSTON,MA 02115
[2] UNIV HOUSTON,DEPT BIOPHYS SCI,HOUSTON,TX 77004
基金
美国国家卫生研究院;
关键词
D O I
10.1016/0024-3205(79)90116-4
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The phosphatidylinositol effect in rat pineal gland (defined as the enhanced incorporation of Pi into phosphatidylinositol which is elicited by agonists) is mediated through alpha-adrenergic receptors. Experiments with glands from animals treated with 6-hydroxydopamine, with dispersed pinealocytes and with a number of relatively specific pre- and postsynaptic alpha-adrenergic agonists and antagonists have shown the receptors involved to be located at postsynaptic sites. © 1979.
引用
收藏
页码:2179 / 2184
页数:6
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