SYNTHESES AND INSULIN-LIKE ACTIVITY OF PHOSPHORYLATED GALACTOSE DERIVATIVES

被引：14

作者：

CARO, HN ^{[1
]}

MARTINLOMAS, M ^{[1
]}

BERNABE, M ^{[1
]}

机构：

[1] CSIC,INST QUIM ORGAN GEN,CARBOHIDRATOS GRP,JUAN DELACIERVA 3,E-28006 MADRID,SPAIN

来源：

CARBOHYDRATE RESEARCH | 1993年 / 240卷

关键词：

D O I：

10.1016/0008-6215(93)84177-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The syntheses of the poly-phosphorylated galactosides 6, 8, 10, 13, 16, and 20, isolated as sodium salts, have been performed. The non-phosphorylated disaccharide 17 and trisaccharide 21 have been prepared via glycosylation of the 2-(trimethylsilyl)ethyl galactosides 3 and 2, respectively, and subsequent complete deprotection. Preliminary insulin-like activity of the phosphorylated derivatives is reported.

引用

页码：119 / 131

页数：13

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