PARATHYROID-HORMONE RELATED PROTEIN IN HYPERCALCEMIA OF HODGKINS-DISEASE

被引：7

作者：

BOLODEOKU, J

BASU, S

LAKHANI, S

DUNNE, F

RATCLIFFE, WA

CLARKE, M

BARRON, JL

机构：

[1] QUEEN ELIZABETH HOSP,WOLFSON RES LABS,BIRMINGHAM B15 2TH,W MIDLANDS,ENGLAND

[2] QUEEN ELIZABETH HOSP,DEPT HAEMATOL,BIRMINGHAM B15 2TH,W MIDLANDS,ENGLAND

[3] QUEEN ELIZABETH HOSP,DEPT MED,BIRMINGHAM B15 2TH,W MIDLANDS,ENGLAND

[4] QUEEN ELIZABETH HOSP,DEPT HISTOPATHOL,BIRMINGHAM B15 2TH,W MIDLANDS,ENGLAND

来源：

JOURNAL OF CLINICAL PATHOLOGY | 1992年 / 45卷 / 06期

关键词：

D O I：

10.1136/jcp.45.6.541

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

The role of parathyroid hormone related protein (PTHRP) as a humoral mediator of hypercalcaemia was investigated in a patient with lymphocyte depleted Hodgkin's disease during an episode of hypercalcaemia, using an immunohistochemical staining technique for PTHRP on the tumour tissue and an immunoradiometric (IRMA) assay for PTHRP1-86 on the patient's plasma. The plasma PTHRP was less than 0.23 pmol/l in the range found in normocalcaemic controls, and the immunohistochemical staining was not positive for protein. PTHRP did not have a role in the pathogenesis of hypercalcaemia in this patient.

引用

页码：541 / 542

页数：2

共 14 条

[1] PARATHYROID-HORMONE RELATED PROTEIN AND HYPERCALCEMIA IN BREAST-CANCER
BUNDRED, NJ
RATCLIFFE, WA
WALKER, RA
COLEY, S
MORRISON, JM
RATCLIFFE, JG
[J]. BRITISH MEDICAL JOURNAL, 1991, 303 (6816) : 1506 - 1509
[2] DANKS JA, 1989, J BONE MINER RES, V4, P273
[3] HODGKINS-DISEASE PRESENTING WITH HYPERCALCEMIA
ELLIS, RD
BECK, PR
MONDAL, BK
[J]. JOURNAL OF CLINICAL PATHOLOGY, 1989, 42 (11) : 1228 - 1228
[4] PARATHYROID-HORMONE-RELATED PROTEIN IN TUMORS ASSOCIATED WITH HYPERCALCEMIA
HEATH, DA
SENIOR, PV
VARLEY, JM
BECK, F
[J]. LANCET, 1990, 335 (8681) : 66 - 69
[5] JACOBSON JO, 1989, CANCER-AM CANCER SOC, V63, P917, DOI 10.1002/1097-0142(19890301)63:5<917::AID-CNCR2820630522>3.0.CO
[6] 2-E
[7] HYPERCALCEMIA IN HODGKINS-DISEASE WITHOUT HYPERPARATHYROIDISM OR SKELETAL METASTASES
MAYNE, KM
BUNCH, C
[J]. JOURNAL OF CLINICAL PATHOLOGY, 1989, 42 (02) : 219 - 219
[8] RECURRENT HYPERCALCEMIA AND ELEVATED 1,25-DIHYDROXYVITAMIN-D LEVELS IN HODGKINS-DISEASE
MERCIER, RJ
THOMPSON, JM
HARMAN, GS
MESSERSCHMIDT, GL
[J]. AMERICAN JOURNAL OF MEDICINE, 1988, 84 (01) : 165 - 168
[9] IMMUNOCYTOCHEMICAL DEMONSTRATION OF PTHRP PROTEIN IN NEOPLASTIC TISSUE OF HTLV-1 POSITIVE HUMAN ADULT T-CELL LEUKEMIA LYMPHOMA - IMPLICATIONS FOR THE MECHANISM OF HYPERCALCEMIA
MOSELEY, JM
DANKS, JA
GRILL, V
LISTER, TA
HORTON, MA
[J]. BRITISH JOURNAL OF CANCER, 1991, 64 (04) : 745 - 748
[10] HYPERCALCEMIA, HODGKINS-DISEASE, AND CALCITRIOL
NEEDLE, MA
CHANDRA, B
[J]. ANNALS OF INTERNAL MEDICINE, 1984, 100 (06) : 916 - 916

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