EFFECT OF FOOD-INTAKE ON INSULIN RECEPTOR IN MAN

被引：27

作者：

DEPIRRO, R ^{[1
]}

BERTOLI, A ^{[1
]}

GRECO, AV ^{[1
]}

GELLI, AS ^{[1
]}

LAURO, R ^{[1
]}

机构：

[1] UNIV CATTOLICA SACRO CUORE,IST PATOL MED,ROME,ITALY

来源：

ACTA ENDOCRINOLOGICA | 1979年 / 90卷 / 03期

关键词：

D O I：

10.1530/acta.0.0900473

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Insulin binding to circulating monocytes was studied in 22 normal volunteers before and 1, 3 and 5 hr after a 1400 Kcal meal. Results indicate that 3 hr after food intake there is an increase in the specific cell binding fraction (P < 0.001) with a change in receptor affinity. Data emerging from the present study demonstrate that there are rapid changes in insulin receptor properties during the day. These changes probably play a role in the regulation of the hormonal and metabolic pattern in normal subjects.

引用

页码：473 / 480

页数：8

共 25 条

[1] POSTPRANDIAL PLASMA GLUCOSE, INSULIN, GLUCAGON AND TRIGLYCERIDE RESPONSES TO A STANDARD DIET IN NORMAL SUBJECTS
AHMED, M
GANNON, MC
NUTTALL, FQ
[J]. DIABETOLOGIA, 1976, 12 (01) : 61 - 67
[2] RAPID TECHNIQUE FOR SEPARATION OF THYMOCYTES FROM SUSPENSIONS BY CENTRIFUGATION THROUGH SILICONE OIL
ANDREASE.PA
SCHAUMBU.BP
OSTERLIN.K
VINTEN, J
GAMMELTO.S
GLIEMANN, J
[J]. ANALYTICAL BIOCHEMISTRY, 1974, 59 (02) : 610 - 616
[3] FLUCTUATIONS IN AFFINITY AND CONCENTRATION OF INSULIN RECEPTORS ON CIRCULATING MONOCYTES OF OBESE PATIENTS - EFFECTS OF STARVATION, REFEEDING, AND DIETING
BAR, RS
GORDEN, P
ROTH, J
KAHN, CR
DEMEYTS, P
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1976, 58 (05) : 1123 - 1135
[4] DIURNAL-VARIATION IN INSULIN BINDING TO HUMAN MONOCYTES
BECKNIELSEN, H
PEDERSEN, O
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1978, 47 (02) : 385 - 390
[5] INSULIN RECEPTOR IN NORMAL AND OBESE PERSONS
BECKNIELSEN, H
PEDERSEN, O
BAGGER, JP
SORENSEN, NS
[J]. ACTA ENDOCRINOLOGICA, 1976, 83 (03): : 565 - 575
[6] BECKNIELSEN H, 1977, DIABETOLOGIA, V13, P589
[7] BOYUM A, 1968, SCAND J CLIN LAB INV, VS 21, P51
[8] INSULIN-RECEPTOR INTERACTIONS IN LIVER CELL MEMBRANES
CUATRECASAS, P
DESBUQUOIS, B
KRUG, F
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1971, 44 (02) : 333 - +
[9] MEMBRANE RECEPTORS
CUATRECASAS, P
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1974, 43 : 169 - 214
[10] CUATRECASAS P, 1971, P NAT ACAD SCI US, V68, P1224

← 1 2 3 →