SURFACE-ENHANCED RAMAN ANALYSIS OF SULFA DRUGS ON COLLOIDAL SILVER DISPERSION

被引：63

作者：

SUTHERLAND, WS ^{[1
]}

LASERNA, JJ ^{[1
]}

ANGEBRANNDT, MJ ^{[1
]}

WINEFORDNER, JD ^{[1
]}

机构：

[1] UNIV FLORIDA,DEPT CHEM,GAINESVILLE,FL 32611

来源：

ANALYTICAL CHEMISTRY | 1990年 / 62卷 / 07期

关键词：

D O I：

10.1021/ac00206a008

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Surface-enhanced Raman spectrometry (SERS) of three sulfa drugs (sulfadiazine, sutfamerazine, and sulfamethazine) Is reported. Silver colloidal dispersions prepared by simple borohydrlde reduction of sliver nitrate are used as substrates. The capability of SERS for spectral fingerprinting of analytes with close structural properties using easily prepared substrates and relatively simple Instrumentation Is illustrated. By careful attention to the timing in the measurement, quantitative Information can be obtained from silver colloids. Linearity was achieved up to 100 ng mL−1. Limits of detection range in the low nanograms per milliliter level. © 1990, American Chemical Society. All rights reserved.

引用

页码：689 / 693

页数：5

共 29 条

[1] SURFACE-ENHANCED RAMAN-SPECTROMETRY OF ORGANOPHOSPHORUS CHEMICAL-AGENTS [J].