INDICATIONS FOR OOCYTE DONATION

被引:8
作者
BARRI, PN
COROLEU, B
MARTINEZ, F
PARERA, N
VEIGA, A
CALDERON, G
BOADA, M
BELIL, I
机构
[1] Service of Reproductive Medicine, Department of Obstetrics and Gynaecology, Institut Universitari Dexeus, Barcelona, 08017
关键词
EMBRYO TRANSFER; INTRAFALLOPIAN TRANSFER; INTRAUTERINE TRANSFER; OOCYTE DONATION; OVARIAN FAILURE;
D O I
10.1093/humrep/7.suppl_1.85
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Donated oocytes were transferred on 92 occasions to 87 women without gonadal function and 5 with functional ovaries. Twenty-three pregnancies were established (25% pregnancy rate), 9 after transfer of fresh embryos in 30 synchronous donor and recipient cycles and 14 after transfers of frozen-thawed embryos in 62 asynchronous donor and recipient cycles. Twenty-two pregnancies were obtained in agonadal patients (25.3% pregnancy rate) and 1 in a gonadal woman (20% pregnancy rate). Pregnant women were younger than those who did not become pregnant, but the difference was not significant. The pregnancy rate was higher when intra-Fallopian transfer was performed (46%) as compared with intrauterine transfer (21.5%) and when micronized progesterone was given intravaginally (pregnancy rate 30.3%) as compared to intramuscularly injected natural progesterone in oil (pregnancy rate 22%). Twenty healthy infants have been born including one set of twins; four pregnancies miscarried.
引用
收藏
页码:85 / 88
页数:4
相关论文
共 18 条
[1]  
Abdalla H.I., Baber R., Kirkland A., Leonard T., Power M., Studd J.W.W., A report on 100 cycles of oocyte donation
[2]  
factors affecting outcome. Hum, Reprod., 5, pp. 1018-1022, (1990)
[3]  
Barri P.N., Coroleu B., Calderdn G., Martinez F., Maristany P., Belil I., Carrera O., Boada M., Arin B., Pascual M.A., Influencia del protocolo de estimulacion en la evolucion de un ciclo de F1V. Proceedings del XIX Congreso de la Sociedat Espagfiola de Fertilidad, Edt. F.J. Rodriguez Escudero. San Sebastidn (Spagila), (1991)
[4]  
Davis O.K., Rosenwaks S., The impact of IVF on the treatment of castrate women, Semin. Reprod. Endocrinol., 8, pp. 313-318, (1990)
[5]  
Devroey P., Braeckmans P., Camus M., Khan J., Smitz J., Staessens C., Van Der Abbeel E., Van Waesberghe L., Wisanto A., Van Steirteghem A.C., Pregnancies after replacement of fresh and frozen-thawed embryos in a donation program, Future Aspects in Human in Vitro Fertilization, pp. 133-137, (1987)
[6]  
Devroey P., Camus M., Van Den Abbeel E., Van Waesberghe L., Wisanto A., Van Steirteghem A.C., Establishment of 22 pregnancies after oocyte and embryo donation, Br. J. Obstet. Gynaecol., 96, pp. 900-906, (1989)
[7]  
Devroey P., Palermo G., Bourgain C., Van Waesberghe L., Smitz J., Van Steirteghem A.C., Progesterone administration in patients with absent ovaries, Int. J. Fertil, 34, pp. 188-193, (1989)
[8]  
Hens L., Devroey P., Van Waesberghe L., Bonduelle M., Van Steirteghem A.C., Liebaers I., Chromosome studies on fertility treatment in women with ovarian failure, Clin. Genet., 36, pp. 81-91, (1989)
[9]  
Kemeter P., Feichtinger W., Bemat E., The willingness of infertile women to donate eggs, Future Aspects in Human in Vitro Fertilization, pp. 145-153, (1987)
[10]  
Laufer N., Navot D., Rabinowitz R., Lewin A., Berkenfeld A., Mangalioth E.J., Schenker J., Pregnancies in the absence of ovaries - Parameters affecting outcome, Future Aspects in Human in Vitro Fertilization, pp. 138-144, (1987)