SITE DIRECTED MUTANTS OF HUMAN INTERLEUKIN-1-ALPHA - A H-1-NMR AND RECEPTOR-BINDING STUDY

被引：13

作者：

GRONENBORN, AM

WINGFIELD, PT

MCDONALD, HR

SCHMEISSNER, U

CLORE, GM

机构：

[1] MAX PLANCK INST BIOCHEM,D-8033 MARTINSRIED,FED REP GER

[2] GLAXO INST MOLEC BIOL,CH-1227 GENEVA,SWITZERLAND

[3] LUDWIG INST CANC RES,CH-1066 EPALINGES,SWITZERLAND

来源：

FEBS LETTERS | 1988年 / 231卷 / 01期

关键词：

D O I：

10.1016/0014-5793(88)80717-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：135 / 138

页数：4

共 14 条

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[4] A H-1-NMR STUDY OF HUMAN INTERLEUKIN-1-BETA - SEQUENCE-SPECIFIC ASSIGNMENT OF AROMATIC RESIDUES USING SITE-DIRECTED MUTANT PROTEINS [J].

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[5]

KRAKAUER T, 1986, CRC CR REV IMMUNOL, V6, P213

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MACDONALD, HR .

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[7] POINT MUTATIONS OF HUMAN INTERLEUKIN-1 WITH DECREASED RECEPTOR-BINDING AFFINITY [J].

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[8] APPLICATION OF PHASE SENSITIVE TWO-DIMENSIONAL CORRELATED SPECTROSCOPY (COSY) FOR MEASUREMENTS OF H-1-H-1 SPIN-SPIN COUPLING-CONSTANTS IN PROTEINS [J].

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[9] EFFICIENT SITE-DIRECTED MUTAGENESIS BY SIMULTANEOUS USE OF 2 PRIMERS [J].

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[10] THERE IS MORE THAN ONE INTERLEUKIN-1 [J].

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