STEREOSELECTIVE TOTAL SYNTHESIS OF RACEMIC STACHENONE

被引：16

作者：

MONTI, SA

YANG, YL

机构：

[1] Department of Chemistry, The University of Texas at Austin, Austin

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1979年 / 44卷 / 05期

关键词：

D O I：

10.1021/jo01319a067

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The C/D ring synthon bicyclo[3.2.1]octenedione (4), available from acid-catalyzed rearrangement of the bicyclo[2.2.2]octenol (7), was converted into the trans-fused B-C/D tricyclic derivative 5 by aldol cyclization and dissolving metal reduction and then into trans-anti-trans tetracyclic diterpene stachenone (1) by Robinson ring annelation and reductive alkylation in an overall yield of 16% from the starting bicyclo[2.2.2]octenone (3). © 1979, American Chemical Society. All rights reserved.

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页码：897 / 898

页数：2

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