TOTAL AND SPECIFIC IGE LEVELS IN PATIENTS WITH ATOPIC-DERMATITIS - CORRELATION BETWEEN PRICK TESTING, CLINICAL HISTORY OF ALLERGY, AND INVITRO QUANTIFICATION OF IGE DURING CLINICAL EXACERBATION AND REMISSION

被引：24

作者：

MACKIE, RM

COBB, SJ

COCHRAN, REI

THOMSON, J

机构：

[1] University Department of Dermatology, Western Infirmary, Glasgow

[2] University Department of Immunology, Western Infirmary, Glasgow

[3] Department of Dermatology, Stobhill Hospital, Glasgow

[4] Department of Dermatology, Royal Infirmary, Glasgow

来源：

CLINICAL AND EXPERIMENTAL DERMATOLOGY | 1979年 / 4卷 / 02期

关键词：

D O I：

10.1111/j.1365-2230.1979.tb01616.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Ten young adults with chronic atopic dermatitis have been followed for up to 18 months through periods of clinical exacerbation and remission. Sequential estimation of total levels of circulating IgE and specific IgE by the radioallergosorbent technique (RAST) showed no significant correlation between IgE levels and severity of skin involvement. However, a clear correlation between clinical history, prick tests and RAST tests was obtained in several cases. Serum IgE levels in seven patients with ‘pure’ atopic dermatitis were elevated to levels similar to those found in three patients with additional respiratory symptoms. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：187 / 195

页数：9