DETERMINATION OF OPTICAL-PROPERTIES OF TURBID MEDIA USING PULSED PHOTOTHERMAL RADIOMETRY

被引:102
作者
PRAHL, SA
VITKIN, IA
BRUGGEMANN, U
WILSON, BC
ANDERSON, RR
机构
[1] HAMILTON REG CANC CTR,HAMILTON L8V 1C3,ONTARIO,CANADA
[2] MCMASTER UNIV,DEPT PHYS,HAMILTON L8V 1C3,ONTARIO,CANADA
关键词
D O I
10.1088/0031-9155/37/6/001
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Pulsed photothermal radiometry (PPTR) measures blackbody radiation emitted by a sample after absorption of an optical pulse. Three techniques for obtaining the absorption coefficient of absorbing-only, semi-infinite samples are examined and shown to give comparable results. An analytic theory for the time dependence of the PPTR signal in semi-infinite scattering and absorbing media has been derived and tested in a series of controlled gel phantoms. This theory, based on the diffusion approximation of the radiative transport equation, is shown to model the time course of the detected signal accurately. Furthermore, when the incident fluence is known, the theory can be used in a non-linear, two-parameter fitting algorithm to determine the absorption and reduced scattering coefficients of a turbid sample with an accuracy of 10-15% for transport albedos ranging from 0.42-0.88.
引用
收藏
页码:1203 / 1217
页数:15
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