STRUCTURE-ACTIVITY RELATIONSHIP IN BENZAMIDES INHIBITING ALCOHOL-DEHYDROGENASE

被引：50

作者：

HANSCH, C

KIM, KH

SARMA, RH

机构：

[1] POMONA COLL, DEPT CHEM, CLAREMONT, CA 91711 USA

[2] SUNY, DEPT CHEM, ALBANY, NY 12203 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1973年 / 95卷 / 19期

关键词：

D O I：

10.1021/ja00800a049

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：6447 / 6449

页数：3

共 12 条

[1] DIRECTIONAL NATURE OF HYDROPHOBIC BONDING IN PHENETHANOLAMINE N-METHYL TRANSFERASE INHIBITORS [J].

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GLAVE, WR .

JOURNAL OF MEDICINAL CHEMISTRY, 1972, 15 (01) :112-&

[2]

HANSCH C, 1972, J BIOL CHEM, V247, P4703

[3] A QUANTITATIVE APPROACH TO BIOCHEMICAL STRUCTURE-ACTIVITY RELATIONSHIPS [J].

HANSCH, C .

ACCOUNTS OF CHEMICAL RESEARCH, 1969, 2 (08) :232-&

[4] USE OF SUBSTITUENT CONSTANTS AND REGRESSION ANALYSIS IN STUDY OF ENZYMATIC REACTION MECHANISMS [J].

HANSCH, C ;

DEUTSCH, EW ;

SMITH, RN .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1965, 87 (12) :2738-&

[5]

Hansch C., 1971, DRUG DESIGN, V1

[6]

KOSHLAND DE, 1960, ENZYMES, V1

[7]

LEFFLER JE, 1964, RATES EQUILIBRIA ORG

[8] PARTITION COEFFICIENTS AND THEIR USES [J].

LEO, A ;

HANSCH, C ;

ELKINS, D .

CHEMICAL REVIEWS, 1971, 71 (06) :525-+

[9] ELECTRONIC, HYDROPHOBIC, AND STERIC EFFECTS OF BINDING OF INHIBITORS TO HORSE LIVER ALCOHOL DEHYDROGENASE-REDUCED PYRIDINE COENZYME BINARY COMPLEX [J].

SARMA, RH ;

WORONICK, CL .

BIOCHEMISTRY, 1972, 11 (02) :170-&

[10]

SHRINER RL, 1964, SYSTEMATIC IDENTIFIC

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