AEROSOL AMPHOTERICIN-B FOR PREVENTION OF INVASIVE PULMONARY ASPERGILLOSIS

被引：62

作者：

BEYER, J

BARZEN, G

RISSE, G

WEYER, C

MIKSITS, K

DULLENKOPF, K

HUHN, D

SIEGERT, W

机构：

[1] FREE UNIV BERLIN,KLINIKUM RUDOLF VIRCHOW,STRAHLENKLIN & POLIKLIN,W-1000 BERLIN 19,GERMANY

[2] FREE UNIV BERLIN,INST MED MIKROBIOL,W-1000 BERLIN 45,GERMANY

[3] TECH UNIV KARLSRUHE,INST THERM STROMUNGSMASCHINEN,W-7500 KARLSRUHE,GERMANY

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1993年 / 37卷 / 06期

关键词：

D O I：

10.1128/AAC.37.6.1367

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The pharmacokinetics and applicability of aerosol amphotericin B administrations were studied in 40 neutropenic patients and 4 healthy volunteers. Particle size was measured and pulmonary deposition was demonstrated by radioisotope studies. Inhalations were easy to administer and were well tolerated, with minimal systemic absorption of the drug.

引用

页码：1367 / 1369

页数：3

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