ANTISENSE TECHNOLOGY - BIOLOGICAL UTILITY AND PRACTICAL CONSIDERATIONS

被引：66

作者：

NECKERS, L

WHITESELL, L

机构：

来源：

AMERICAN JOURNAL OF PHYSIOLOGY | 1993年 / 265卷 / 01期

关键词：

D O I：

10.1152/ajplung.1993.265.1.L1

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Antisense RNA and DNA techniques have been developed as a relatively recent approach to the specific modulation of gene expression in vitro and in vivo. This review discusses general considerations for the application of antisense techniques. We shall examine the relative advantages and disadvantages of DNA versus RNA techniques, as well as the common pitfalls peculiar to each strategy.

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页码：L1 / L12

页数：12

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