TREATMENT OF CHRONIC IDIOPATHIC URTICARIA WITH COMBINED H-1 AND H-2 BLOCKERS

被引：61

作者：

PHANUPHAK, P

SCHOCKET, A

KOHLER, PF

机构：

[1] Department of Medicine, Division of Clinical Immunology, University of Colorado Medical Center, Denver, Colorado

来源：

CLINICAL ALLERGY | 1978年 / 8卷 / 05期

关键词：

D O I：

10.1111/j.1365-2222.1978.tb01493.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Combined H1 (cyproheptadine) and H2 antihistamines (cimetidine) were tried in eight patients with chronic urticaria who were previously unresponsive to conventional anti‐urticarial regimens, including type I antihistamines, hydroxyzine, ephedrine and corticosteroids. 50 % of the patients responded with 90 % or greater improvement within 10 days. The remaining 50% showed no benefit. Side effects of the medications were minimal. These results indicate that a 10 day trial of both H1 and H2 antihistamines may be useful in patients with chronic urticaria resistant to all other standard treatment modalities. Copyright © 1978, Wiley Blackwell. All rights reserved

引用

页码：429 / 433

页数：5

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