MAINTENANCE OF 24 HOUR EATING RHYTHMICITY DURING GOLD THIOGLUCOSE INDUCED HYPOTHALAMIC HYPERPHAGIA IN RATS

被引：13

作者：

RIETVELD, WJ ^{[1
]}

TENHOOR, F ^{[1
]}

KOOIJ, M ^{[1
]}

FLORY, W ^{[1
]}

机构：

[1] STATE UNIV LEIDEN,DEPT PHYSIOL PSYCHOL,LEIDEN,NETHERLANDS

来源：

PHYSIOLOGY & BEHAVIOR | 1979年 / 22卷 / 03期

关键词：

Circadian rhythms; Feeding behavior; Gold thioglucose; Hyperphagia; Hypothalamus;

D O I：

10.1016/0031-9384(79)90024-6

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

Lesion were made in the ventromedial hypothalamic area in rats by implantation of cannulas filled with gold thioglucose. Whenever this local application of gold thioglucose resulted in hyperphagia, all animals retained their 24 hr eating rhythm. Although there was an increase in food intake, the ratio of nighttime eating activity to the total 24 hr eating activity remained the same. This supports the hypothesis that cells which are involved in the 24 hr rhythm in eating activity are different from those responsible for the regulation of food intake. © 1979.

引用

页码：549 / 553

页数：5

共 27 条

[1]

AHLSKOG JE, 1975, SCIENCE, V190, P399, DOI 10.1126/science.1179221

[2] HYPOTHALAMIC BLOOD FLOW FOLLOWING GOLDTHIOGLUCOSE-INDUCED LESIONS [J].

AREES, EA ;

VELTMAN, BI ;

MAYER, J .

EXPERIMENTAL NEUROLOGY, 1969, 25 (03) :410-&

[3] FEEDING PATTERNS OF NORMAL AND VENTROMEDIAL HYPOTHALAMIC LESIONED MALE AND FEMALE RATS [J].

BALAGURA, S ;

DEVENPOR.LD .

JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY, 1970, 71 (03) :357-&

[4] A STUDY OF THE EFFECT OF HYPOTHALAMIC LESIONS ON THE EATING HABITS OF THE ALBINO RAT [J].

BROOKS, CM ;

LOCKWOOD, RA ;

WIGGINS, ML .

AMERICAN JOURNAL OF PHYSIOLOGY, 1946, 147 (04) :735-741

[5] THE RELATIVE IMPORTANCE OF CHANGES IN ACTIVITY IN THE DEVELOPMENT OF EXPERIMENTALLY PRODUCED OBESITY IN THE RAT [J].

BROOKS, CM .

AMERICAN JOURNAL OF PHYSIOLOGY, 1946, 147 (04) :708-716

[6]

Cowan W., 1970, CONT RES METHODS NEU

[7] GOLD THIOGLUCOSE DAMAGE TO SATIETY CENTER - INHIBITION IN DIABETES [J].

DEBONS, AF ;

KRIMSKY, I ;

LIKUSKI, HJ ;

FROM, A ;

CLOUTIER, RJ .

AMERICAN JOURNAL OF PHYSIOLOGY, 1968, 214 (03) :652-&

[8] GOLD THIOGLUCOSE INDUCTION OF OBESITY - SIGNIFICANCE OF FOCAL GOLD DEPOSITS IN HYPOTHALAMUS [J].

DEBONS, AF ;

KRIMSKY, I ;

FROM, A ;

CLOUTIER, RJ .

AMERICAN JOURNAL OF PHYSIOLOGY, 1970, 219 (05) :1403-&

[9] SITE OF ACTION OF GOLD THIOGLUCOSE IN HYPOTHALAMIC SATIETY CENTER [J].

DEBONS, AF ;

KRIMSKY, I ;

FROM, A ;

CLOUTIER, RJ .

AMERICAN JOURNAL OF PHYSIOLOGY, 1970, 219 (05) :1397-&

[10]

DIXON KC, 1965, NEUROHISTOCHEMISTRY, P558

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