STEREOSELECTIVE OXIDATIVE SPIROKETALIZATION OF A C-ARYLGLUCAL DERIVED FROM PALLADIUM-CATALYZED COUPLING - SYNTHESIS OF THE C-ARYLGLUCOSIDE SPIROKETAL NUCLEUS OF THE PAPULACANDINS

被引：60

作者：

FRIESEN, RW

STURINO, CF

机构：

[1] Department of Chemistry, University of Toronto, Lash Miller Chemical Laboratories, Toronto, Ontario

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 23期

关键词：

D O I：

10.1021/jo00310a004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

: The synthesis of the C-arylglucoside tricyclic spiroketal nucleus of the papulacandins 5b was achieved utilizing two key steps, namely the palladium-catalyzed coupling of the aryl bromide 6 and the stannyl glucal 2 and stereoselective oxidative spiroketalization of the derived C-arylglucal 7. © 1990, American Chemical Society. All rights reserved.

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页码：5808 / 5810

页数：3

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