TRANSNEURONAL EFFECTS TRIGGERED BY SAPHENOUS NERVE INJURY ON ONE SIDE OF A RAT ARE RESTRICTED TO NEURONS OF THE CONTRALATERAL, HOMOLOGOUS NERVE

被引：33

作者：

KOLSTON, J ^{[1
]}

LISNEY, SJW ^{[1
]}

MULHOLLAND, MNC ^{[1
]}

PASSANT, CD ^{[1
]}

机构：

[1] UNIV WALK,SCH MED SCI,DEPT PHYSIOL,BRISTOL BS8 1TD,ENGLAND

来源：

NEUROSCIENCE LETTERS | 1991年 / 130卷 / 02期

基金：

英国惠康基金;

关键词：

PERIPHERAL NERVE INJURY; PLASMA EXTRAVASATION; NEUROGENIC INFLAMMATION; TRANSNEURONAL SIGNALS;

D O I：

10.1016/0304-3940(91)90393-8

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Transection and regeneration of the saphenous nerve on one side of a rat reduces the ability of the contralateral saphenous nerve to evoke plasma extravasation following antidromic nerve stimulation. It is proposed that a transneuronal signal - that is a signal that passes from injured neurones on one side of the body to intact ones on the other via the spinal cord - is involved in triggering this response. The present experiments have shown that the influence of this transneuronal signal is restricted to neurones of homologous nerves on the two sides of an animal, i.e. it passes from saphenous nerve neurones on one side to saphenous nerve neurones on the other; its influence does not seem to extend to neurones in other nerves, for example ones in either the ipsi- or contralateral sural nerves.

引用

页码：187 / 189

页数：3

共 10 条

[1] SAPHENOUS NERVE INJURY AND REGENERATION ON ONE SIDE OF A RAT SUPPRESSES THE ABILITY OF THE CONTRALATERAL NERVE TO EVOKE PLASMA EXTRAVASATION
ALLNATT, JP
DICKSON, KE
LISNEY, SJW
[J]. NEUROSCIENCE LETTERS, 1990, 118 (02) : 219 - 222
[2] SYMPATHETIC AND AFFERENT SOMATA PROJECTING IN HINDLIMB NERVES AND THE ANATOMICAL ORGANIZATION OF THE LUMBAR SYMPATHETIC NERVOUS-SYSTEM OF THE RAT
BARON, R
JANIG, W
KOLLMANN, W
[J]. JOURNAL OF COMPARATIVE NEUROLOGY, 1988, 275 (03) : 460 - 468
[3] BRENAN A, 1988, J ANAT, V157, P57
[4] DECREASE OF SUBSTANCE-P IN PRIMARY AFFERENT NEURONS AND IMPAIRMENT OF NEUROGENIC PLASMA EXTRAVASATION BY CAPSAICIN
GAMSE, R
HOLZER, P
LEMBECK, F
[J]. BRITISH JOURNAL OF PHARMACOLOGY, 1980, 68 (02) : 207 - 213
[5] HUGHES S, 1989, J CHEM NEUROANAT, V2, P227
[6] FUNCTIONAL-ASPECTS OF THE REGENERATION OF UNMYELINATED AXONS IN THE RAT SAPHENOUS NERVE
LISNEY, SJW
[J]. JOURNAL OF THE NEUROLOGICAL SCIENCES, 1987, 80 (2-3) : 289 - 298
[7] SYNAPSE FORMATION IN INTACT INNERVATED CUTANEOUS-PECTORIS MUSCLES OF THE FROG FOLLOWING DENERVATION OF THE OPPOSITE MUSCLE
ROTSHENKER, S
[J]. JOURNAL OF PHYSIOLOGY-LONDON, 1979, 292 (JUL): : 535 - 547
[8] THE TRANS-NEURONAL INDUCTION OF SPROUTING AND SYNAPSE FORMATION IN INTACT MOUSE MUSCLES
ROTSHENKER, S
TAL, M
[J]. JOURNAL OF PHYSIOLOGY-LONDON, 1985, 360 (MAR): : 387 - &
[9] SZOLCSANYI J, 1984, ANTIDROMIC VASODILAT, P7
[10] WIESENFELDHALLIN Z, 1989, EXP BRAIN RES, V76, P88

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