BOVINE PAPILLOMAVIRUS E1 PROTEIN CAN, BY ITSELF, EFFICIENTLY DRIVE MULTIPLE ROUNDS OF DNA-SYNTHESIS IN-VITRO

被引:34
作者
BONNEANDREA, C
SANTUCCI, S
CLERTANT, P
机构
关键词
D O I
10.1128/JVI.69.5.3201-3205.1995
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Bovine papillomavirus E1 protein was found to be as efficient as the simian virus 40 large T antigen in initiating DNA synthesis in a cell-free system derived from COS1 cells. Multiple rounds of DNA synthesis occur, initiated at the bovine papillomavirus type 1 origin. Therefore, E1 functions in vitro as a lytic virus initiator.
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页码:3201 / 3205
页数:5
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