ULTRASTRUCTURE OF EXPERIMENTAL NERVE TUMOURS

被引:14
作者
GEORGSSON, G
WESSEL, W
THOMAS, C
机构
[1] Institut für Neuropathologie, Pathologisches Institut der Universität Bonn, Bonn
[2] Institute for Experimental Pathology, University of Iceland, Reykjavik, Keldur
来源
ZEITSCHRIFT FUR KREBSFORSCHUNG | 1969年 / 72卷 / 01期
关键词
D O I
10.1007/BF00524787
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Six malignant nerve tumours of rats induced by oral N-nitroso-N-methyl-urea were studied electron microscopically. The ultrastructure of these experimental tumours was, in spite of a marked anaplasia, essentially similar to the ultrastructure of human neurinomas; thus these tumours can be regarded as equivalent to human neurinomas. The findings support the opinion that neurinomas arise from Schwannian cells. Morphometric measurements in these anaplastic tumours revealed a high value for the volume of the granular endoplasmic reticulum, although the most poorly differentiated tumours showed clearly a decrease of the granular endoplasmic reticulum and concomitantly an increased volume of the mitochondria. © 1969 Springer-Verlag.
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页码:12 / +
页数:1
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