PREPARATION OF BETA-AMINOESTERS FROM KETENE SILYL ACETALS AND N-(ALKYLAMINO)BENZOTRIAZOLES

被引：18

作者：

KATRITZKY, AR

SHOBANA, N

HARRIS, PA

机构：

[1] Department of Chemistry, University of Florida, Gainesville

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 28期

关键词：

D O I：

10.1016/S0040-4039(00)94482-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A wide variety of β-aminoesters are prepared in good yields by the reaction of lithium ester enolates derived from ketene silyl acetals with N-(alkylamino)benzotriazoles. The secondary β-aminoesters readily cyclize to β-lactams (2-azetidinones) on deprotonation. © 1990.

引用

页码：3999 / 4002

页数：4

共 15 条

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[4] JONES JH, 1979, COMPREHENSIVE ORGA 6, V2, P834
[5] THE CHEMISTRY OF N-SUBSTITUTED BENZOTRIAZOLES .11. THE PREPARATION OF 1-(ALPHA-AMINOALKYL)-BENZOTRIAZOLES IN AQUEOUS-SOLUTION
KATRITZKY, AR
PILARSKI, B
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[J]. ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 1989, 21 (02) : 135 - 139
[6] KATRITZKY AR, 1989, SYNTHESIS-STUTTGART, P747
[7] KATRITZKY AR, 1990, TETRAHEDRON, P987
[8] KATRITZKY AR, 1988, J CHEM SOC P1, P225
[9] MUKERJEE AK, 1973, SYNTHESIS-STUTTGART, P327
[10] OJIMA I, 1977, TETRAHEDRON LETT, P3643

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