FIBROBLAST FUNCTION AND THE MAINTENANCE OF THE AORTIC-VALVE MATRIX

被引：35

作者：

VANDERKAMP, AWM ^{[1
]}

NAUTA, J ^{[1
]}

机构：

[1] ERASMUS UNIV,DEPT THORAC & CARDIOVASC SURG,ROTTERDAM,NETHERLANDS

来源：

CARDIOVASCULAR RESEARCH | 1979年 / 13卷 / 03期

关键词：

D O I：

10.1093/cvr/13.3.167

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Summary: The long-term behaviour of the aortic-valve allograft seems to be dependent on the maintenance of its matrix. Protein and collagen synthesis was studied in rat aortic-valves. Quantitative and qualitative methods proved the production of at least two protein pools. One protein pool is localised intracellularily with a 'turn-over' time of about 2 weeks, and a second pool is localised extracellularily with a 'turn-over' time of at least 8 weeks. The latter protein pool mainly consists of collagen.

引用

页码：167 / 172

页数：6

共 31 条

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