IMMUNE-RESPONSE IN HOSTS WITH CADAVERIC DURAL GRAFTS - REPORT OF 2 CASES

被引：39

作者：

ALLEYNE, CH ^{[1
]}

BARROW, DL ^{[1
]}

机构：

[1] EMORY UNIV, SCH MED, DEPT NEUROSURG, ATLANTA, GA USA

来源：

JOURNAL OF NEUROSURGERY | 1994年 / 81卷 / 04期

关键词：

DURA MATER; IMMUNE RESPONSE; DURAL GRAFT;

D O I：

10.3171/jns.1994.81.4.0610

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The use of cadaveric human dura has been critical in the repair of dural defects since the dawn of neurosurgery. Reports in the literature of immune response to this type of graft have been extremely rare. Two patients are presented who received cadaveric dural implants with resulting meningeal signs and cerebrospinal fluid eosinophilia several weeks after surgery. Peripheral eosinophilia was present in one patient. The signs and symptoms resolved temporarily during corticosteroid therapy and permanently upon removal of the offending grafts. These cases illustrate that an immune-type reaction can occur with significant morbidity in patients receiving cadaveric dural grafts. A proposed mechanism for this response is discussed.

引用

页码：610 / 613

页数：4

共 38 条

[1]

Abbe R., 1895, T AM SURG ASS, V13, P490

[2]

Abbott W M, 1972, Surg Forum, V23, P282

[3] ABSENCE OF ANTIGENICITY IN FREEZE-DRIED SKIN ALLOGRAFTS [J].