A TOTAL SYNTHESIS OF (-)-SLAFRAMINE FROM (+)-CIS-(2R,3S)-3-HYDROXYPROLINE

被引：29

作者：

KNIGHT, DW

SIBLEY, AW

机构：

[1] Department of Chemistry, Nottingham, NG7 2RD, University Park

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 41期

关键词：

D O I：

10.1016/0040-4039(93)88117-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A total synthesis of the naturally occurring indolizidine (-)-Slaframine 4 has been achieved, starting from the cis-3-hydroxyproline derivative 1, in which a key step is a Julia olefination reaction using the dianion derived from the beta-aminosulfone 5.

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页码：6607 / 6610

页数：4

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