PROGRESSIVE BRAIN-STEM AND WHITE-MATTER LESIONS IN KEARNS-SAYRE SYNDROME - A CASE-REPORT

被引：18

作者：

NAKAGAWA, E ^{[1
]}

HIRANO, S ^{[1
]}

YAMANOUCHI, H ^{[1
]}

GOTO, Y ^{[1
]}

NONAKA, I ^{[1
]}

TAKASHIMA, S ^{[1
]}

机构：

[1] NATL CTR NEUROL & PSYCHIAT,NATL INST NEUROSCI,DIV MENTAL RETARDAT & BIRTH DEFECT RES,KODAIRA,TOKYO 187,JAPAN

来源：

BRAIN & DEVELOPMENT | 1994年 / 16卷 / 05期

关键词：

KEARNS-SAYRE SYNDROME; MRI; MITOCHONDRIAL DNA; FLAIR SEQUENCE;

D O I：

10.1016/0387-7604(94)90133-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We performed serial cranial MRI examinations on an 11-year-old boy with Kearns-Sayre syndrome. Proton density (PD)-, T-2-weighted and T-2-weighted fluid attenuated inversion recovery (FLAIR) sequences revealed progressive high signal intensity areas in the brainstem, globus pallidus, thalamus, and white matter of the cerebrum and cerebellum bilaterally. The probable gliotic lesions in the brainstem may be part of the neurogenic origin of the external ophthalmoplegia in addition to the primary defect of the extraocularmuscle in KSS.

引用

页码：416 / 418

页数：3

共 10 条

[1]

Coene BD, 1993, NEURORADIOLOGY, V35, P327

[2] SPONGIFORM ENCEPHALOPATHY WITH CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA - CENTRAL OPHTHALMOPLEGIA MIMICKING OCULAR MYOPATHY [J].