EXPRESSION OF CAENORHABDITIS-ELEGANS MESSENGER-RNA IN XENOPUS-OOCYTES - A MODEL SYSTEM TO STUDY THE MECHANISM OF ACTION OF AVERMECTINS

被引：24

作者：

ARENA, JP

机构：

[1] Merck Research Laboratories, Department of Cell Biochemistry and Physiology, Rahway

来源：

PARASITOLOGY TODAY | 1994年 / 10卷 / 01期

关键词：

D O I：

10.1016/0169-4758(94)90357-3

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

It has recently been shown that Xenopus oocytes injected with mRNA from the free-living nematode Caenorhabditis elegans express avermectin-sensitive chloride channels(1). Joseph Arena here reviews whet is known about the mechanism of action of avermectin and how these recent results relate to the mechanism in nematodes.

引用

页码：35 / 37

页数：3

共 29 条

[1] EXPRESSION OF A GLUTAMATE-ACTIVATED CHLORIDE CURRENT IN XENOPUS-OOCYTES INJECTED WITH CAENORHABDITIS-ELEGANS RNA - EVIDENCE FOR MODULATION BY AVERMECTIN
ARENA, JP
LIU, KK
PARESS, PS
SCHAEFFER, JM
CULLY, DF
[J]. MOLECULAR BRAIN RESEARCH, 1992, 15 (3-4): : 339 - 348
[2] ARENA JP, 1991, MOL PHARMACOL, V40, P368
[3] ACTIONS OF INSECTICIDES ON THE INSECT GABA RECEPTOR COMPLEX
BERMUDEZ, I
HAWKINS, CA
TAYLOR, AM
BEADLE, DJ
[J]. JOURNAL OF RECEPTOR RESEARCH, 1991, 11 (1-4): : 221 - 232
[4] Campbell WC, 1989, IVERMECTIN ABAMECTIN
[5] CULLY DF, 1991, MOL PHARMACOL, V40, P326
[6] CULLY DF, 1993, J CELL BIOCHEM, P115
[7] DAVIS RE, 1989, J NEUROSCI, V9, P403
[8] ACTIONS OF DIHYDROAVERMECTIN-B1A ON INSECT MUSCLE
DUCE, IR
SCOTT, RH
[J]. BRITISH JOURNAL OF PHARMACOLOGY, 1985, 85 (02) : 395 - 401
[9] INTEGRATIVE TRANSFORMATION OF CAENORHABDITIS-ELEGANS
FIRE, A
[J]. EMBO JOURNAL, 1986, 5 (10) : 2673 - 2680
[10] FLEMING JT, 1991, J PHYSIOL-LONDON, V438, pP371

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