REACTIVITY OF CHLORONITROBENZENES TOWARDS GLUTATHIONE UNDER PHYSIOLOGICAL CONDITIONS - THE RELATIONSHIP BETWEEN STRUCTURE AND REACTION-RATE

被引：8

作者：

HULBERT, PB

HAMOODI, NM

机构：

[1] Pharmaceutical Chemistry, School of Pharmacy, University of Bradford, Bradford

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 1990年 / 8卷 / 8-12期

关键词：

1-CHLORO-2,4-DINITROBENZENE; GLUTATHIONE CONJUGATIONS; STRUCTURE-ACTIVITY RELATIONSHIP (QSAR; SAR); HAMMETT CONSTANTS; HAMMETT RELATIONSHIP; QUANTITATIVE; CHLORONITROBENZENES;

D O I：

10.1016/0731-7085(90)80161-H

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An excellent quantitative structure-reactivity correlation between the structural features of CDNB analogues (as expressed by their electronic substituent constants) and the non-enzymic reactivity of these analogues with GSH has been discovered. © 1990.

引用

页码：1009 / 1013

页数：5