ONTOGENY OF ADRENERGIC AROUSAL AND CHOLINERGIC INHIBITORY MECHANISMS IN RAT

被引：356

作者：

CAMPBELL, BA

LYTLE, LD

FIBIGER, HC

机构：

[1] Department of Psychology, Princeton University, Princeton

来源：

SCIENCE | 1969年 / 166卷 / 3905期

关键词：

D O I：

10.1126/science.166.3905.635

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

With spontaneous activity as a measure of arousal, dose response curves were established for scopolamine and amphetamine administered to 10-, 15-, 20-, 25-, and 100-day-old rats. Amphetamine always increased activity, but scopolamine had no effect on younger rats, which suggests that adrenergic excitatory areas in the brainstem mature more rapidly than cholinergic inhibitory areas in the forebrain.

引用

页码：635 / &

共 31 条

[1] AGAJANIAN GK, 1967, BRAIN RES, V6, P716
[2] ONTOGENY OF BEHAVIOUR IN ALBINO RAT
BOLLES, RC
WOODS, PJ
[J]. ANIMAL BEHAVIOUR, 1964, 12 (04) : 427 - &
[3] THE EFFECTS OF SOME DRUGS ON THE ELECTRICAL ACTIVITY OF THE BRAIN
BRADLEY, PB
ELKES, J
[J]. BRAIN, 1957, 80 (01) : 77 - 117
[4] THE HIERARCHICAL ORGANIZATION OF THE CENTRAL NERVOUS-SYSTEM - IMPLICATIONS FOR LEARNING-PROCESSES AND CRITICAL PERIODS IN EARLY DEVELOPMENT
BRONSON, G
[J]. BEHAVIORAL SCIENCE, 1965, 10 (01): : 7 - 25
[5] Campbell B. A., 1964, THIRST
[6] CLEMENTE C D, 1968, Conditional Reflex, V3, P145
[7] DELL P, 1963, BRAIN MECHANISMS
[8] THE NATURE OF APRAXIA
DENNYBROWN, D
[J]. JOURNAL OF NERVOUS AND MENTAL DISEASE, 1958, 126 (01) : 9 - 32
[9] DEVELOPMENT OF CORTICAL ELECTRICAL ACTIVITY IN RAT
DEZA, L
EIDELBERG, E
[J]. EXPERIMENTAL NEUROLOGY, 1967, 17 (04) : 425 - +
[10] INFLUENCE OF CENTRALLY ACTING CHOLINOLYTIC DRUGS ON BRAIN ACETYLCHOLINE LEVELS
GIARMAN, NJ
PEPEU, G
[J]. BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1964, 23 (01): : 123 - +

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