CHRONIC STRESS-INDUCED CHANGES IN LOCUS COERULEUS NEURONAL-ACTIVITY

被引：71

作者：

PAVCOVICH, LA ^{[1
]}

CANCELA, LM ^{[1
]}

VOLOSIN, M ^{[1
]}

MOLINA, VA ^{[1
]}

RAMIREZ, OA ^{[1
]}

机构：

[1] NATL UNIV CORDOBA,FAC CIENCIAS QUIM,DEPT FARM,SUCURSAL 16-CC 61,RA-5016 CORDOBA,ARGENTINA

来源：

BRAIN RESEARCH BULLETIN | 1990年 / 24卷 / 02期

关键词：

Alpha[!sub]2[!/sub] adrenoceptors sensitivity; Locus coeruleus; Single unit recording; Stress;

D O I：

10.1016/0361-9230(90)90219-P

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Locus coeruleus (LC) activity was assessed in rats exposed to either acute or chronic stress. After one immobilization session, the number of spontaneously active LC neurons dramatically decreased. On the other hand, repeated restraint sessions enhanced noradrenergic (NA) transmission and the inhibitory effect of clonidine (CLON) was greater on these cells than in those of controls. These results bear on the adaptive changes in the NA system following acute or chronic stress. © 1990.

引用

页码：293 / 296

页数：4

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