XLMR GENES - UPDATE 1990

被引：40

作者：

NERI, G

GURRIERI, F

GAL, A

LUBS, HA

机构：

[1] UNIV BONN, INST HUMANGENET, W-5300 BONN, GERMANY

[2] UNIV MIAMI, DEPT PEDIAT, DIV GENET, MIAMI, FL 33152 USA

来源：

AMERICAN JOURNAL OF MEDICAL GENETICS | 1991年 / 38卷 / 2-3期

关键词：

MENTAL RETARDATION; X-CHROMOSOME; LINKAGE; FRAGILE-X;

D O I：

10.1002/ajmg.1320380204

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We have identified 39 X-linked conditions in which mental retardation seems to be the primary characteristic, although pathogenesis is unknown. These conditions can be subdivided into syndromal and non-syndromal, depending on the existence of a recognizable pattern of minor anomalies and/or malformations, or lack thereof. Seventeen genes have been regionally mapped onto the X chronosome. However, in 14 instances the data were derived from a single family and most lod scores were less than 3.0.

引用

页码：186 / 189

页数：4

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