DISTRIBUTION OF AMYGDALA INPUT TO THE NUCLEUS-ACCUMBENS-SEPTI - AN ELECTROPHYSIOLOGICAL INVESTIGATION

被引：39

作者：

CALLAWAY, CW ^{[1
]}

HAKAN, RL ^{[1
]}

HENRIKSEN, SJ ^{[1
]}

机构：

[1] Scripps Res Inst, RES INST, DEPT PRECLIN NEUROSCI, 10666 N TORREY PINES RD, LA JOLLA, CA 92037 USA

来源：

JOURNAL OF NEURAL TRANSMISSION-GENERAL SECTION | 1991年 / 83卷 / 03期

关键词：

AMYGDALA; HIPPOCAMPUS; NUCLEUS ACCUMBENS; ELECTROPHYSIOLOGY;

D O I：

10.1007/BF01253391

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The nucleus accumbens septi (NAS) receives afferent input from the amygdala via the stria terminalis and from the hippocampus via the fimbria. Extracellular recordings from 196 NAS neurons in halothane-anesthetized rats revealed heterogeneous response patterns following stimulation of the amygdala. The observation that 30% of anterior NAS units but only 16% of posterior NAS units were responsive to amygdala stimulation suggested a topographical arrangement of amygdala efferents. Comparing the effects of amygdala and fimbria stimulation revealed that the two afferent pathways converge onto individual NAS neurons. The present results clarify the topographical distribution of amygdala input to the NAS, confirm that inputs from two limbic structures are integrated within the NAS, and further illustrate the electrophysiological heterogeneity of NAS neurons.

引用

页码：215 / 225

页数：11

共 26 条

[1] EXCITATORY AMINO-ACID PROJECTIONS TO THE NUCLEUS-ACCUMBENS-SEPTI IN THE RAT - A RETROGRADE TRANSPORT STUDY UTILIZING D[H-3] ASPARTATE AND [H-3] GABA
CHRISTIE, MJ
SUMMERS, RJ
STEPHENSON, JA
COOK, CJ
BEART, PM
[J]. NEUROSCIENCE, 1987, 22 (02) : 425 - 439
[2] AUTORADIOGRAPHIC TRACING OF NUCLEUS ACCUMBENS EFFERENTS IN RAT
CONRAD, LCA
PFAFF, DW
[J]. BRAIN RESEARCH, 1976, 113 (03) : 589 - 596
[3] CONVERGENCE OF EXCITATORY AMYGDALOID AND HIPPOCAMPAL INPUT IN THE NUCLEUS ACCUMBENS SEPTI
DEFRANCE, JF
MARCHAND, JE
STANLEY, JC
SIKES, RW
CHRONISTER, RB
[J]. BRAIN RESEARCH, 1980, 185 (01) : 183 - 186
[4] DOPAMINE ACTION IN THE NUCLEUS-ACCUMBENS
DEFRANCE, JF
SIKES, RW
CHRONISTER, RB
[J]. JOURNAL OF NEUROPHYSIOLOGY, 1985, 54 (06) : 1568 - 1577
[5] PROJECTION FIELD OF STRIA TERMINALIS IN RAT-BRAIN - EXPERIMENTAL STUDY
DEOLMOS, JS
INGRAM, WR
[J]. JOURNAL OF COMPARATIVE NEUROLOGY, 1972, 146 (03) : 303 - +
[6] SUB-CORTICAL AFFERENTS OF THE NUCLEUS ACCUMBENS SEPTI IN THE CAT, STUDIED WITH RETROGRADE AXONAL-TRANSPORT OF HORSERADISH-PEROXIDASE AND BIS-BENZIMID
GROENEWEGEN, HJ
BECKER, NEHM
LOHMAN, AHM
[J]. NEUROSCIENCE, 1980, 5 (11) : 1903 - 1916
[7] A THEORY OF THE FUNCTIONAL-ORGANIZATION OF THE NEOSTRIATUM AND THE NEOSTRIATAL CONTROL OF VOLUNTARY MOVEMENT
GROVES, PM
[J]. BRAIN RESEARCH REVIEWS, 1983, 5 (02) : 109 - 132
[8] SYSTEMIC OPIATE ADMINISTRATION HAS HETEROGENEOUS EFFECTS ON ACTIVITY RECORDED FROM NUCLEUS-ACCUMBENS NEURONS INVIVO
HAKAN, RL
HENRIKSEN, SJ
[J]. NEUROSCIENCE LETTERS, 1987, 83 (03) : 307 - 312
[9] Heimer L., 1975, GOLGI CENTENNIAL S, P177
[10] CELL CLUSTERS IN THE NUCLEUS ACCUMBENS OF THE RAT, AND THE MOSAIC RELATIONSHIP OF OPIATE RECEPTORS, ACETYLCHOLINESTERASE AND SUBCORTICAL AFFERENT TERMINATIONS
HERKENHAM, M
EDLEY, SM
STUART, J
[J]. NEUROSCIENCE, 1984, 11 (03) : 561 - 593

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