NOV - A NEW GENETIC-LOCUS THAT AFFECTS THE RESPONSE OF ESCHERICHIA-COLI K-12 TO NOVOBIOCIN

被引：8

作者：

RAKONJAC, J

MILIC, M

AJDICPREDIC, D

SANTOS, D

IVANISEVIC, R

SAVIC, DJ

机构：

[1] INST MOLEC GENET & GENET ENGN, VOJVODE STEPE 282, POB 794, YU-11000 BELGRADE, YUGOSLAVIA

[2] UNIV OXFORD, INST MOLEC MED, IMPERIAL CANC RES FUND, OXFORD OX2 9DU, ENGLAND

来源：

MOLECULAR MICROBIOLOGY | 1992年 / 6卷 / 11期

关键词：

D O I：

10.1111/j.1365-2958.1992.tb00876.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have identified a new gene locus (nov) affecting the resistance of Escherichia coli K-12 to novobiocin. The gene also affects, although to a lesser extent, tolerance to another gyrase inhibitor coumermycin. Transductional and complementation analysis show that nov is located between attO80 and the osmZ (hns) genes at minute 27 of the E. coli K-12 genetic map. In standard laboratory strains of E. coli K-12 nov exists at least in two allelic forms.

引用

页码：1547 / 1553

页数：7

共 37 条

[1]

APPLEYARD RK, 1954, GENETICS, V39, P440

[2] PEDIGREES OF SOME MUTANT STRAINS OF ESCHERICHIA-COLI K-12 [J].